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Other outcomes that were described in Affiliation with using topical (dermal) formulations of metronidazole include things like pores and skin irritation, transient skin erythema, and delicate pores and skin dryness and burning. None of those adverse gatherings exceeded an incidence of two% of clients.
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Information from well-managed trials instantly evaluating metronidazole administered orally to metronidazole administered vaginally are certainly not out there.
Fertility scientific tests have been done in mice up to 6 situations the encouraged human oral dose (dependant on mg/m²) and possess revealed jnetoto no evidence of impaired fertility.
Oral metronidazole has been noted to potentiate the anticoagulant outcome of warfarin and various coumarin anti‑coagulants, leading to a prolongation of prothrombin time.
Apply the medication in a skinny layer and rub in fully. You may apply cosmetics soon after using metronidazole topical.
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No fetotoxicity was noticed immediately after oral administration of metronidazole in pregnant rats or mice; obtainable info usually do not permit calculation of related comparisons between systemic exposures of metronidazole noticed in animal reports to systemic exposures that will be envisioned in individuals immediately after topical use of this drug
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